Year : 2017 | Volume
: 17 | Issue : 3 | Page : 105-
Consultant Transplant Surgeon, Sheffield Teaching Hospitals Senior Lecturer (Hon), University of Sheffield-University of Liverpool, United Kingdom
|How to cite this article:|
Halawa A. Editorial comment.J Egypt Soc Nephrol Transplant 2017;17:105-105
|How to cite this URL:|
Halawa A. Editorial comment. J Egypt Soc Nephrol Transplant [serial online] 2017 [cited 2018 Jan 22 ];17:105-105
Available from: http://www.jesnt.eg.net/text.asp?2017/17/3/105/219246
It is a great pleasure to share with you the summary of international guidelines. We felt it is useful for transplant professionals to keep up-to-date with the different management strategies of post-transplant infection. We aimed by this summary to cover a wide spectrum of these infectious diseases, their diagnosis, prevention, and treatment.
Of course, you are aware that post-transplant infections are the leading cause of hospitalization in transplant recipients that can lead to significant morbidity and mortality. The risk is determined by epidemiologic exposure, immunosuppressive therapy, and prophylaxis.
It is always a challenge to identify and treat these infections promptly. The suppressed immune system in these patients makes the cardinal clinical picture such as fever, rigors and rise in the inflammatory markers unusual and, often, late signs. Also, these patients usually fail to mount an antibody response to make the standard serological diagnosis possible; hence high index of suspicion is crucial and could be lifesaving. Moreover, utilization of special tests including certain invasive diagnostic techniques, imaging, and nucleic acid based assays is often mandatory to reach an accurate diagnosis in prompt timing. Nucleic acid-based assays are sensitive, rapid, and allow detection of subclinical infection and assessment of response to therapy. Preventive steps include the screening of donors and recipients and vaccination.
We hope that this work guides the management of post-transplant infectious diseases and increase the awareness of these disastrous complications.