|Year : 2017 | Volume
| Issue : 4 | Page : 137
Erratum: Correlations of serum magnesium with dyslipidemia in patients on maintenance hemodialysis
|Date of Web Publication||17-Jan-2018|
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
. Erratum: Correlations of serum magnesium with dyslipidemia in patients on maintenance hemodialysis. J Egypt Soc Nephrol Transplant 2017;17:137
|How to cite this URL:|
. Erratum: Correlations of serum magnesium with dyslipidemia in patients on maintenance hemodialysis. J Egypt Soc Nephrol Transplant [serial online] 2017 [cited 2018 Dec 11];17:137. Available from: http://www.jesnt.eg.net/text.asp?2017/17/4/137/223415
The article titled “Correlations of serum magnesium with dyslipidemia in patients on maintenance hemodialysis”, published on pages 8-29, Issue 1, Volume 17 of Journal of The Egyptian Society of Nephrology and Transplantation , the article abstract was incorrect. The correct abstract of the article should be read as:
| Background|| |
High LP-a indicates a coagulant risk for plaque thrombosis. Thus, it predicts risk for early atherosclerosis independently of other cardiac risk factors in patients with CKD. This study aimed to determine the correlation of serum Mg with dyslipidemia in patients on maintenance HD.
| Patients and methods|| |
This case–control study was conducted on 37 ESRF patients on MHD who were recruited from the renal Unit, Internal Medicine Department, Assuit University Hospitals, Egypt from 2010 to 2012. In addition, 25 apparently healthy persons were enrolled as a control group. The study was approved by the ethical committee of the Faculty of Medicine. The duration of HD ranged from 5to15years. The type of dialyzer membrane was polysulfone with bicarbonate dialysate. Patients were excluded if they had been taking diuretics and/or lipid lowering agents. All participants were subjected to thorough history taking and full clinical examination. Peripheral hemogram, liver function, kidney function, lipid profile, LP-a, serum Ca,phosphorus (P), and Mg were assessed. An ECG and ECHO were also performed.
| Results|| |
Significant high levels of TG and LP-a with significant low levels of HDL-C and LDL-C were seen. Significant high levels of Mg were observed among our patients. LVH was a striking finding in patients who had more serum Mg and LP-a with normal QTc interval and ST-segment in ECG. Strong associations of Mg and LPa with lipid profile were found. In the multivariate logistic regression analysis; a 45-fold increase in the probability of HD per 1mg/dl increase in the Mg level [OR =45, 95% CI: 15.4–68.1, P<0.01]. Mg level revealed a 14% increase in the prediction level in the study with 68% increase in the probability of HD per 1mg/dl increase in the level of LP-a (OR=1.68, 95% CI: 1.01–2.3, P<0.05) . LP-a revealed a 6% excess in the prediction of HD. Also a 3% decrease in the probability of HD per 1mg/dl decrease in the level of LDL (OR=0.97, 95% CI: 0.95–0.99, P<0.05) with 5% increase in its predictive level was found.
| Conclusion|| |
High serum LP-a level correlates with CV mortality in CKD patients. Mg has a protective role in hypertension, atherosclerosis, and vascular calcification in ESRD patients. Notably, Mg depletion may be an independent risk factor for premature death in CKD patients.
| References|| |
Tony EA, Tohamy MA, Amin NF, Abdel-Aal AM, Rahim SA. Correlations of serum magnesium with dyslipidemia in patients on maintenance hemodialysis. J Egypt Soc Nephrol Transplant 2017; 17:8–29. [Full text]